Abstract Background O-fucosyltransferase1 (OFUT1) is a conserved ER protein essential for Notch signaling.OFUT1 glycosylates EGF domains, which can then be further modified by the N-acetylglucosaminyltransferase Fringe.OFUT1 also possesses a chaperone activity that promotes the folding and secretion of Notch.Here, we investigate the respective cont
From archaeological excavations, huge quantities of material are recovered, usually in the form of fragments.Their correct interpretation and classification are laborious and time-consuming and requires measurement, analysis and comparison of several items.Basing these activities on quantitative methods that process 3D digital data from experimenta
Soilless cultivation represent a valid opportunity for the agricultural production sector, especially in areas characterized by severe soil degradation and limited water availability.Furthermore, this agronomic practice embodies a favorable response toward an environment-friendly agriculture and a promising tool in the vision of a general challenge
For wet disk clutches, the energy input is strongly influenced by its friction behavior.However, the friction behavior cannot be simulated and therefore is mostly derived The Border South from experimental data for specific clutch systems.This paper presents a new approach for the identification and validation of linear friction models using analys
Osteosarcoma is a highly aggressive cancer common in children and adolescents.There is still a lack of effective treatments for metastatic or recurrent osteosarcoma.The role of long non-coding RNAs (lncRNAs) in Nutritional knowledge, attitudes and behaviours in rugby league; influences of age, body composition and ancestry osteosarcoma has graduall